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The San Francisco 49ers could be underdogs virtually the entire season.

Posted by Niners Nation: A San Francisco 49ers Blog on

Lines for 49ers first 15 games have them as underdogs or pick 'em across the board

CG Technology has the lines for Weeks 1-16 of the 2016 NFL season. They will change plenty, but this is an interesting starting point. The 49ers are underdogs most of the season.
ninersnation.com

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